the biological activity and composition of the essential oil of sclerorhachis leptoclada (asteraceae-anthemideae) from iran
نویسندگان
چکیده
the biological activity and composition of the essential oil of sclerorhachis leptoclada rech. an endemic species from northeast of iran was studied. the essential oil was isolated from the aerial flowering parts of the plant and analyzed by gc and gc-ms. fifty-four compounds accounting for 95.9% of the total oil were characterized. the main constituents were (e)-nerolidol (14.5%), terpinen-4-ol (13.3%), camphor (6.1%), 1,8-cineole (4.8%) and p-cymene (4.5%). the antimicrobial activity of the essential oil of s. leptoclada was tested against eight microbial strains and a fungi. the results of the bioassays showed that the gram-positive bacteria, bacillus subtilis and staphylococcus epidermidis, were the most sensitive to the oil than others with the mic value of 1.8 mg/ml. the tested fungi, saccharomyces cerevisiae was highly inhibited by the oil of s. leptoclada with mic value of 10 mg/ml. in the case of cytotoxicity, ic50 values estimated to be 312, 1250, 625 and 1250 μg oil/ml respectively, for the vero, sw480, mcf7, and jet 3 cancer cell lines.
منابع مشابه
The Biological Activity and Composition of the Essential Oil of Sclerorhachis leptoclada (Asteraceae-Anthemideae) from Iran
The biological activity and composition of the essential oil of Sclerorhachis leptoclada Rech. an endemic species from northeast of Iran was studied. The essential oil was isolated from the aerial flowering parts of the plant and analyzed by GC and GC-MS. Fifty-four compounds accounting for 95.9% of the total oil were characterized. The main constituents were (E)-nerolidol (14.5%), terpinen-4-o...
متن کاملThe Biological Activity and Composition of the Essential Oil of Sclerorhachis leptoclada (Asteraceae-Anthemideae) from Iran
The biological activity and composition of the essential oil of Sclerorhachis leptoclada Rech. an endemic species from northeast of Iran was studied. The essential oil was isolated from the aerial flowering parts of the plant and analyzed by GC and GC-MS. Fifty-four compounds accounting for 95.9% of the total oil were characterized. The main constituents were (E)-nerolidol (14.5%), terpinen-4-o...
متن کاملThe Biological Activity and Composition of the Essential Oil of Sclerorhachis leptoclada (Asteraceae-Anthemideae) from Iran
The biological activity and composition of the essential oil of Sclerorhachis leptoclada Rech. f. an endemic species from northeast of Iran was studied. The essential oil was isolated from the aerial flowering parts of the plant and analyzed by GC and GC-MS. Fifty-four compounds accounting for 95.9% of the total oil were characterized. The main constituents were (E)-nerolidol (14.5%), terpinen-...
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Antimicrobial Activity and Composition of the Essential Oil of Cymbopogon Olivieri (Boiss.) Bor from Iran
The in vitro antimicrobial activity of the essential oil isolated from the aerial parts of Cymbopogon Olivieri (Boiss.) Bor, an aromatic grass of Iran was tested against three Gram-negative and four Gram-positive bacteria and also three fungi. The results of the bioassays showed that the oil has a remarkable antimicrobial activity. Bacillus subtilis and Candida albicans were more sensitive to t...
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The chemical composition of the essential oil obtained from the aerial parts of Laurus nobilis L. has been examined by gas chromatography (GC) and GC- mass spectrometery (MS). The main components of the oil were identified. 1,8-Cineole was the major component in the oil together with b-terpinyl acetate, terpinene-4-ol, a-pinene, b-pinene, p-cymene, linalool and ...
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عنوان ژورنال:
iranian journal of pharmaceutical researchجلد ۱۳، شماره ۳، صفحات ۱۰۹۷-۱۱۰۴
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